News

Congatulations to Dr. Hasti Shafie for defending her thesis on nanaoparticle filtration in the kidneys. The whole lab is so proud of her!

Congratulation to Dr. Xuhui Ning, Dr. Mengxiao Yu, and Dr. Jie Zheng for their publication in Advanced Materials. Gold Nanoparticle Transport in the Injured Kidneys with Elevated Renal Function Biomarkers explores the relationship between renal function biomarkers and the transport of renal-clearable gold nanoparticles throughout kidney disease progression using a cisplatin injury model. This research shows the potential of AuNPs for non-invasive imaging of kidneys while highlighting the potential utilizing AuNPs in damaged kidney.

To read the abstract or see the full article, click below!

Gold Nanoparticle Transport in the Injured Kidneys with Elevated Renal Function Biomarkers

Congratulations to Yingyu Huang, Mengxiao Yu, and Jie Zheng for having their research article Charge barriers in the kidney elimination of engineered nanoparticles published in the Proceedings of the National Academy of Sciences of the USA! Through their research, it was found that the movement of charged particles is regulated by the peritubular capillaries and proximal tubules of the kidney.

By identifying these two critical charge-dependent barriers in the renal transport of nanoparticles, our findings offer a fundamental insight for the design of renal nanomedicines tailored for selective targeting within the kidney, laying down a foundation for developing targeting renal nanomedicines for future kidney disease management in the clinics.

Charge barriers in the kidney elimination of engineered nanoparticles

Read the full article here:

Charge barriers in the kidney elimination of engineered nanoparticles | PNAS

Members of the Zheng Lab watched the total solar eclipse today! The next total solar eclipse in the US wont be until 2044 – in 20 years!

Congratulations to Yi Luo for being accepted into the UT Southwestern – UTD joint program for Biomedical Engineering!

Congratulations to Yingu Huang, Xuhui Ning, Samira Ahrari, Mengxiao Yu, and Jie Zheng for having their work published in Nature Reviews Nephrology! This review article, Physiological principles underlying the kidney targeting of renal nanomedicines, covers what is currently known about the distribution, transport, and clearance of nanoparticles in the kidney, providing a necessary base of information to further research kidney disease and treatment via nanomedicines.

To read the abstract of this article, click the link below!

Physiological principles underlying the kidney targeting of renal nanomedicines | Nature Reviews Nephrology

Undergraduate students Johnathan Bai and Annabelle Rice were selected as URSA recipients after submitting a research proposal last semester! They will be competing at the URSA Poster competition on April 16th.

Mozhdeh Ghafari has recently joined our lab as a graduate student! Mozhdeh graduated from Ishafan University of Technology in Iran with a B.S. in Applied Chemistry and has previously worked in pharmacology and drug delivery.

Follow the link below to see Mozhdeh’s profile!

Mozhdeh Ghafari – Zheng’s Lab (utdallas.edu)