Publications

 

Inyang KE, Szabo-Pardi T, Wentworth E, McDougal TA, Dussor G, Burton MD*, Price TJ*. The antidiabetic drug metformin prevents and reverses neuropathic pain and spinal cord microglial activation in male but not female mice. Pharmacol Res. 2018 Nov 1;139:1-16. doi: 10.1016/j.phrs.2018.10.027. [Epub ahead of print] * co-corresponding authors

Garner KM, Amin R, Johnson RW, Scarlett EJ, Burton, MD. Microglia priming by interleukin-6 signaling is enhanced in aged mice. Journal of Neuroimmunology. 2018 September 10; (online). doi:10.1016/j.jneuroim.20185.09.002

Udit S, Burton MD, Rutkowski JM, Lee S, Bookout AL, Scherer PE, Elmquist JK, Gautron L. Na(v)1.8 neurons are involved in limiting acute phase responses to dietary fat. Mol Metab. 2017 Oct;6(10):1081-1091. doi:10.1016/j.molmet.2017.07.012.

Burton MD, Tillu DV, Mazhar K, Mejia GL, Asiedu MN, Inyang K, Hughes T, Lian B, Dussor G, Price TJ. Pharmacological activation of AMPK inhibits incision-evoked mechanical hypersensitivity and the development of hyperalgesic priming in mice. Neuroscience. 2017 Sep 17;359:119-129. doi:10.1016/j.neuroscience.

Moy JK, Khoutorsky A, Asiedu MN, Black BJ, Kuhn JL, Barragán-Iglesias P, Megat S, Burton MD, Burgos-Vega CC, Melemedjian OK, Boitano S, Vagner J, Gkogkas CG, Pancrazio JJ, Mogil JS, Dussor G, Sonenberg N, Price TJ. The MNK-eIF4E Signaling Axis Contributes to Injury-Induced Nociceptive Plasticity and the Development of Chronic Pain. J Neurosci. 2017 Aug 2;37(31):7481-7499. doi:10.1523/JNEUROSCI.0220-17.2017.

Burton MD, Rytych JL, Amin R, Johnson RW. Dietary Luteolin Reduces Proinflammatory Microglia in the Brain of Senescent Mice. Rejuvenation Res. 2016 Aug;19(4):286-92. doi: 10.1089/rej.2015.1708.

Elmore MR, Burton MD, Conrad MS, Rytych JL, Van Alstine WG, Johnson RW. Respiratory viral infection in neonatal piglets causes marked microglia activation in the hippocampus and deficits in spatial learning. J Neurosci. 2014 Feb 5;34(6):2120-9. doi: 10.1523/JNEUROSCI.2180-13.2014.

Gautron L, Rutkowski JM, Burton MD, Wei W, Wan Y, Elmquist JK. Neuronal and nonneuronal cholinergic structures in the mouse gastrointestinal tract and spleen. J Comp Neurol. 2013 Nov;521(16):3741-67. doi: 10.1002/cne.23376.

Conrad MS, Elmore MR, Burton MD, Rytych JL, Johnson RW. Early-life viral infection causes neuroinflammation, cognitive deficits, and changes in neurogenesis in the neonatal piglet. Brain, Behavior, and Immunity 2013 32, e8

Burton MD, Rytych JL, Freund GG, Johnson RW. Central inhibition of interleukin-6 trans-signaling during peripheral infection reduced neuroinflammation and sickness in aged mice. Brain Behav Immun. 2013 May;30:66-72. doi: 10.1016/j.bbi.2013.01.002.

Rytych JL, Elmore MR, Burton MD, Conrad MS, Donovan SM, Dilger RN, Johnson RW. Early life iron deficiency impairs spatial cognition in neonatal piglets. J Nutr. 2012 Nov;142(11):2050-6. doi: 10.3945/jn.112.165522.

Burton MD, Johnson RW. Interleukin-6 trans-signaling in the senescent mouse brain is involved in infection-related deficits in contextual fear conditioning. Brain Behav Immun. 2012 Jul;26(5):732-8. doi: 10.1016/j.bbi.2011.10.008.

Burton MD, Sparkman NL, Johnson RW. Inhibition of interleukin-6 trans-signaling in the brain facilitates recovery from lipopolysaccharide-induced sickness behavior. J Neuroinflammation. 2011 May 19;8:54. doi:10.1186/1742-2094-8-54

Sparkman NL, Burton MD, Heyen JR, Beverly JL, Johnson RW. Mice deficient in interleukin-6 are refractory to lipopolysaccharide-induced disruption in working memory.  Brain, Behavior, and Immunity 2006; 19 (4), e66-e67