Congratulations to Yingyu Huang, Mengxiao Yu, and Jie Zheng for having their research article Charge barriers in the kidney elimination of engineered nanoparticles published in the Proceedings of the National Academy of Sciences of the USA! Through their research, it was found that the movement of charged particles is regulated by the peritubular capillaries and proximal tubules of the kidney.
By identifying these two critical charge-dependent barriers in the renal transport of nanoparticles, our findings offer a fundamental insight for the design of renal nanomedicines tailored for selective targeting within the kidney, laying down a foundation for developing targeting renal nanomedicines for future kidney disease management in the clinics.
Charge barriers in the kidney elimination of engineered nanoparticles
Read the full article here:
Charge barriers in the kidney elimination of engineered nanoparticles | PNAS