Publications

1. S. Shukla, W. Chen, S. Rao, S. Yang, C. Ou, K. P. Larsen, G. Hummer, P. I. Hanson, J. H. Hurley. Mechanism and cellular function of direct membrane binding by the ESCRT and ERES-associated Ca²⁺-sensor ALG-2. Proc. Natl. Acad. Sci. U.S.A. 121, e2318046121 (2024). DOI: 10.1073/pnas.2318046121.

2. K. Rose, T. Jepson, S. Shukla, A. M. Romero, M. Kampmann, K. Xu, J. H. Hurley. Tau fibrils induce nanoscale membrane damage and nucleate cytosolic tau at lysosomes. Proc. Natl. Acad. Sci. U.S.A. 121, e2315690121 (2024). DOI: 10.1073/pnas.2315690121

3. S. Shukla, K. P. Larsen, C. Ou, K. Rose, J. H. Hurley. In vitro reconstitution of calcium-dependent recruitment of the human ESCRT machinery in lysosomal membrane repair. Proc. Natl. Acad. Sci. U.S.A. 119, e2205590119 (2022). DOI: 10.1073/pnas.2205590119

4. S. Shukla, T. Baumgart. Enzymatic trans-bilayer lipid transport: Mechanisms, efficiencies, slippage, and membrane curvature. Biochimica et Biophysica Acta (BBA)-Biomembranes 1863, 183534 (2021). DOI: 10.1016/j.bbamem.2020.183534

5. S. Shukla, R. Jin, J. Robustelli, Z. E. Zimmerman, T. Baumgart. PIP2 reshapes membranes through asymmetric desorption. Biophysical Journal 117, 962-974 (2019). DOI: 10.1016/j.bpj.2019.07.047