Publications – Gassensmith Lab

A Self-Adjuvanting Large Pore 2D Covalent Organic Framework as a Vaccine Platform

Y. H. Wijesundara, N. Arora, R. N. Ehrman, T. S. Howlett, T. M. Weyman, I. Trashi, O. Trashi, S. Kumari, S. D. Diwakara, W. Tang, M. C. Senarathna, K. H. Drewniak, Z. Wang, R. A. Smaldone, J. J. Gassensmith, Angew. Chem. Int. Ed. 2024, e202413020. [HTML][PDF]

Dually Functionalized Dendrimer for Stimuli-Responsive Release of Active Ingredients into the Skin

O. Trashi, N. Satish, I. Trashi, L. M. H., Y. H. Wijesundara, C. Hu, F. C. Herbert, R. A. Smaldone, J. J. Gassensmith, Acta Biomater., Article ASAP 2024 [HTML][PDF]

Testing the Antigenic Potential of Transmembrane Proteins to Develop a Thermostable Tuberculosis MOF-Liposomal Vaccine

S. Kumari^#, J. Martinez-Garcia^#, R. N. Ehrman, W. Tang, J. Miles, P. Basak, T. S. Howlett, Y. H. Wijesundara, Z. Wang, A. Izzo, B. Restrepo, L. Lu, G. Meloni^*, and J. J. Gassensmith* ACS Infect. Dis. 2024 Article ASAP. [HTML][PDF]

Mn and Zn-Doped Multivariate Metal-Organic Framework as a Metalloimmunological Adjuvant to Promote Protection Against Tuberculosis Infection

T. S. Howlett, S. Kumari, R. N. Ehrman, J. Masson, L. Izzo, T. Wang, H. Gull, I. Trashi, W. Tang, O. Trashi, N. Satish, Y. H. Wijesundara, F. C. Herbert, A. A. Izzo, J. J. Gassensmith, . Adv. Healthcare Mater. 2024, 2402358. [HTML] [PDF]

How Should Journals Address a Procedure that Turns out to be Dangerous?

O. Trashi, N. Satish, T-Q Nguyen, J. J. Gassensmith*, M.B. Mulcahy* “How Should Journals Address a Procedure that Turns out to be Dangerous?” ACS Chem. Health Saf. 2024 Just Accepted. [HTML][PDF] Selected as an ACS Editor’s Choice!

TEMPO-Conjugated Tobacco Mosaic Virus as a Magnetic Resonance Imaging Contrast Agent for Detection of Superoxide Production in the Inflammed Liver

J. L. Lumata^#, L. M. Hagge^#, M A. Gaspar, I Trashi, R N. Ehrman, S. Koirala, A. C. Chiev, Y. H. Wijesundara, C. B. Darwin, S. Pena, X. Wen, J. Wansapura, S. O. Nielsen, Z. Kovacs, L. L. Lumata, J. J. Gassensmith* J. Mat. Chem. B. 2024 ,12, 3273-3281 [HTML][PDF]

The Promise and Potential of Metal-Organic Frameworks and Covalent Organic Frameworks in Vaccine Nanotechnology

Y. H. Wijesundara#, T. S. Howlett#, S. Kumari#, J. J. Gassensmith* Chem. Rev., 2024, Chem. Rev. 2024 124, 6, 3013-3036.[HTML][PDF]

A Scalable Synthesis of Adjuvanting Antigen Depots Based on Metal-Organic Frameworks

R. N. Ehrman^#, O. R. Brohlin^#, Y. H. Wijesundara, S. Kumari, O. Trashi, T S. Howlett, I. Trashi, F. C. Herbert, Arun Raja, S. Koirala, N. Tran, N. M. Al-Kharji, W. Tang, M. C. Senarathn, L. M. Hagge, R.A. Smaldone, J. J. Gassensmith* Chem. Sci., 2024, 15, 2731 – 2744 [HTML][PDF]