News

Congratulations Dr. Yingyu and Dr. Mengxiao! Their paper, “Proximal tubules eliminate endocytose gold nanoparticles through an organelle-extrusion-mediated self-renewal mechanism” was published by Nature Nanotech

In April 2023, Yingyu, Mengxiao, and Dr. Zheng published a new paper on a previously unknown mechanism by which the proximal tubular eliminates waste.

Congratulations to Samira for passing her PhD thesis defense!

Samira successfully defended her thesis on June 7th 2023 and is now a PhD. We are so happy for her!

Group members celebrate after Samira’s defense. From L to right: Wei Xiao, Hasti (Arefeh) Shafie, Dr. Samira Ahrari, Dr. Mengxiao Yu, Dr. Zheng, Dr. Yingyu Huang
Dr. Jie Zheng and Dr. Samira Ahrari
Left to Right: Dr. Yingyu Huang, Dr. Louis Ning, Yi Luo, Sophia Zinn, Dr. Jie Zheng, Dr. Samira Ahrari, Hasti Shafie, Dr. Mengxiao Yu, Wei Xiao

New Partnership with UT Southwestern!

In May, we toured the Texas Instruments Biomedical Engineering and Sciences Building at UT Southwestern where we will have a new lab opening in August. We are very excited to collaborate with UT Southwestern Medical Center and to work in this beautiful building on the East Campus of UTSW Medical Center.

“This new facility will deepen the collaboration between UT Southwestern and UT Dallas to advance transformational bioengineering research to improve patient care. By integrating biomedical engineering with advances in related fields such as artificial intelligence, molecular imaging, robotics, and genetic engineering, the UTSW-UTD collaborations will further solidify North Texas as a hub for biomedical innovation,” said Daniel K. Podolsky, M.D., President of UT Southwestern Medical Center, who holds the Philip O’Bryan Montgomery, Jr., M.D. Distinguished Presidential Chair in Academic Administration and the Doris and Bryan Wildenthal Distinguished Chair in Medical Science.

Group members were able to tour the facility wearing hard hats. From L to R: Mengxiao Yu, Sophia Zinn, Hasti Arefeh, Samira Ahrari

Old News (Feb 2018- Nov 2021)

November 2021: Qinhan and Siqing passed their PhD thesis defense! Congratulations and couldn’t be more happy for you!

August 2021: Wei Xiao joined our group as a graduate student! Welcome!

June 2021: Samira passed her PhD qualifying examination! Congrats!

September 2020: Xingya and Qinhan’s paper “Noninvasive monitoring of hepatic glutathione depletion through fluorescence imaging and blood testing.” was published by Science Advances. Great Job! (Highlighted by UT Dallas News: Study Shows Simple Blood Test Could Detect Liver Injury Earlier | News Center (utdallas.edu))

September 2020: Bujie’s paper “Hyperfluorescence imaging of kidney cancer enabled by renal secretion pathway dependent efflux transport.” was published by Angew. Chem. Int. Ed.  Good Job!

August 2020: Yingyu passed his PhD thesis defense! Congratulations and happy graduation!

June 2020: Chuanqi and Yingyu’s review paper “Renal clearable nanocarriers: Overcoming the physiological barriers for precise drug delivery and clearance.” was published by Journal of Controlled Release.  Good Job!

May 2020: Hasti Shafie joined our group as a graduate student! Welcome!

April 2020: Xingya’s paper “Cancer photothermal therapy with ICG-conjugated gold nanoclusters.” was published by Bioconjugate Chemistry.  Great Job!

April 2020: Shaoheng and Yingyu’s paper “Salivary Excretion of Renal-Clearable Silver Nanoparticles.” was published by Angew. Chem. Int. Ed.  Congratulations!

March 2020: Dr. Zheng was selected to the AIMBE College of Fellows!Congratulations, Dr.Zheng! (News from the AIMBE: Jie Zheng Dr. Jie Zheng Inducted into AIMBE College of Fellows – AIMBE)

March 2020: Dr. Mengxiao Yu received her first NIH R01 grant that focuses on fundamental understanding of the transport and interactions of engineered nanoparticles in the renal proximal tubules. Congratulations! NIH Awards $1.4 Million for Research on Kidney-Safe Nanomedicines – Office of Research and Innovation (utdallas.edu)

December 2019: Chuanqi’s paper “In situ ligand-directed growth of gold nanoparticles in biological tissues.” was published by Nano Letters.  Good Job!

November 2019: Bujie’s paper “Tailoring kidney transport of organic dyes with low-molecular-weight PEGylation.” was published by Bioconjugate Chemistry.Congratulations!

August 2019: Bujie, Xingya and Chuanqi passed their PhD thesis defense! Congratulations to you all and happy graduation!

July 2019: Xingya’s paper “Glutathione-mediated biotransformation in the liver modulates nanoparticle transport was published by Nature Nanotechnology.  Great Job! (Highlighted by UT Dallas News Center: Chemists Close Gap in Making Nanomedicines Safer, More Efficient – News Center | The University of Texas at Dallas (utdallas.edu))

May 2019: Chuanqi’s paper “Tuning in vivo transport of anticancer drugs with renal clearable gold nanoparticles.” was accepted by Angew. Chem. Int. Ed.Congratulations!

May 2019: Congratulations to Bujie for receiving Chinese Government award for outstanding self-financed students aboard. Good job!

April 2019: Bujie’s received IKA Graduate Research Leadership Fellowship Award. Congratulations!

March 2019: Xingya’s paper “Photoacoustic Imaging of Nanoparticle Transport in the Kidneys at High Temporal Resolution” was published by Angew. Chem. Int. Ed. Good job!

December 2018: Dr. Mengxiao Yu was highlighted by Nanomedicine (Lond) as a female scientist in the field of developing nanomedicines and imaging nanotechnology for kidney disease. Congratulations Dr. Yu! How nanotechnology imaging can be used in kidney disease: an interview with Dr Mengxiao Yu | Nanomedicine (futuremedicine.com)

November 2018:  Samira Ahrari joined our group as a graduate student. Welcome!

September 2018: Mengxiao paper “Renal Clearable Luminescent Gold Nanoparticles: From the Bench to the Clinics” was published by Angew. Chem. Int. Ed. Congratulations!

September 2018: Xingya’s paper “Ultrasmall noble metal nanoparticles: Breakthroughs and biomedical implications” was pubulished by Nano today. Well done!

June 2018: Bujie’s paper “Transport and Interactions of Nanoparticles in the Kidneys” was accepted by Nature Reviews Materials. Great job!

May 2018: Prof. Dr. Zheng received Cecil H. and Ida Green Professor fellowship in Systems Biology Science. Congratulations! 

May 2018: Shaoheng’s paper “Antibacterial Activity of Silver Nanoparticles: Structural Effects ” was published by Advanced healthcare materialsWell done!

March 2018: Yingyu’s paper “Luminescence mechanisms of ultrasmall gold nanoparticles ” was published by Dalton TransactionsCongratulations! 

Feburary 2018: Congratulations to Mr. Qinhan Zhou for passing his qualifying exam. Good job!