Hyperpolarized 13C and metabolic imaging

  1. “Metabolism of Hyperpolarized [1-13C]pyruvate through Alternate Pathways in Rat Liver”, E. Jin, KX Moreno, J-X Wang, L Fidelino, ME Merritt, AD Sherry & CR Malloy, NMR Biomed, 29, 466-476 (2016).

 

  1. “Accelerated chemical shift imaging of hyperpolarized 13C metabolites”, JX Wang, ME Merritt, AD Sherry, & CR Malloy, Magn Reson Med, 76, 1033-1038 (2016).

 

  1. “Biochemical specificity in human cardiac imaging by 13C magnetic resonance imaging”, CR Malloy & AD Sherry, Circulation Research, 119, 1146-1148 (2016).

 

  1. “An oral load of [13C3]glycerol and blood NMR analysis detects fatty acid esterification, pentose phosphate pathway and glycerol metabolism through the tricarboxylic acid cycle in human liver”, ES Jin, AD Sherry & CR Malloy, J Biol Chem, 291, 19031-19041 (2016).

 

  1. “Integrating 13C Isotopomer Methods with Hyperpolarization for a Comprehensive Picture of Metabolism”, AD Sherry & CR Malloy (2016) in Handbook of Magnetic Resonance Spectroscopy In Vivo: MRS Theory, Practice and Applications, Bottomley, P.A. and Griffiths, J.R. (eds). John Wiley & Sons Ltd, Chichester, UK, pp 679-698.

 

  1. “A general chemical shift decomposition method for hyperpolarized 13C metabolite magnetic resonance imaging”, J-X Wang, ME Merritt, AD Sherry & CR Malloy, Magn Reson Chem, DOI 10.1002/mrc.4435 (2016).

 

  1. “Measuring cerebral glucose metabolism in the healthy mouse using hyperpolarized 13C magnetic resonance”, M Mishkovsky, B Anderson, M Karlsson, MH Lerche, AD Sherry, R Gruetter, Z Kovacs, & A Comment, Science Reports, 7, 1179 (2017).

 

  1. “Hyperpolarized d-[1-13C]gluconolactone as a probe of the pentose phosphate pathway”, KX Moreno, CE Harrison, ME Merritt, Z Kovacs, CR Malloy, & AD Sherry, NMR Biomed, 30: e3713 (2017).

 

  1. “A Novel Inhibitor of Pyruvate Dehydrogenase Kinase Stimulates Myocardial Carbohydrate Oxidation in Diet-Induced Obesity”, C-Y Wu, S Satapati, W Gui, RM Wynn, G Sharma, M Lou, X Qi, SC Burgess, CR Malloy, C Khemtong, AD Sherry, DT Chuang, & ME Merritt, J. Biol. Chem., 293, 9604-9613 (2018).

 

  1. “tcaSIM: A simulation program for optimal design of 13C tracer experiments for analysis of metabolic flux by NMR and mass spectrometry”, JR Alger, AD Sherry & CR Malloy, Current Metabolomics, 6, 176-187 (2018).

 

  1. “Metabolism of hyperpolarized 13C-acetoacetate to β-hydroxybutyrate detects real-time mitochondrial redox and dysfunction in heart tissue”, W Chen, G Sharma, W Jiang, NR Maptue, CR Malloy, AD Sherry & C Khemtong, NMR in Biomed., 2019 Jun;32(6):e4091. doi: 10.1002/nbm.4091. Epub 2019 Apr 10. PMID: 30968985.

 

  1. “Probing carbohydrate metabolism using hyperpolarized 13C-labeled molecules”, J Singh, EH Suh, G Sharma, C Khemtong, AD Sherry, & Zoltan Kovacs, NMR in Biomed., 2018 Nov 26:e4018. doi: 10.1002/nbm.4018. PMID: 30474153.

 

  1. “Esterase-catalyzed production of hyperpolarized 13C-enriched carbon dioxide in tissues for measuring pH”, NR Maptue, W Jiang, C Harrison, AM Funk, G Sharma, CR Malloy, AD Sherry & C Khemtong, ACS Sensors, 2018 Nov 26;3(11):2232-2236. doi: 10.1021/acssensors.8b01097

 

  1. “In vivo assessment of increased oxidation of branched-chain amino acids in glioblastoma”, EH Suh, EP Hackett, RM Wynn, DT Chuang, B Zhang, W Luo, AD Sherry & JM Park, Sci. Reports, 9:340 (2019). doi: 10.1038/s41598-018-37390-0. PMID: 30674979.

 

  1. “New Insights into Metabolic Regulation from Hyperpolarized 13C MRS/MRI Studies”, AD Sherry & CR Malloy, Chapter in book edited by Tom Jue on HP metabolic imaging, in press.