Imaging projects (new agents and animal MRI)

  1. “pH imaging of mouse kidneys in vivo using a frequency-dependent paraCEST agent”, Y Wu, S Zhang, TC Soesbe, J Yu, E Vinogradov, RE Lenkinski & AD Sherry AD, Magn Reson Med., 75, 2432-2441 (2016).

 

  1. “Zinc-sensitive MRI contrast agent detects differential release of Zn(II) ions from the healthy versus malignant mouse prostate,” MV Clavijo-Jordan, S-T Lo, S Chen, C Preihs, S Chirayil, S Zhang, W-H Li, P Kapur, LM De Leon-Rodriguez, AJM Lubag, NM Rofsky & AD Sherry, Proc Natl Acad Sci, USA, 113, E5464-E5471 (2016).

 

  1. “The relationship between NMR chemical shifts of thermally polarized and hyperpolarized 89Y complexes and their solution structures”, Y Xing, AK Jindal, M Regueiro-Figueroa, M Le Fur, N Kervarec, P Zhao, Z Kovacs, L Valencia, P Pérez-Lourido, R Tripier, D Esteban-Gómez, C Platas-Iglesias & AD Sherry, Chem. Eur. J., 22, 16657-16667 (2016).

 

  1. “Imaging extracellular lactate in vitro and in vivo using CEST MRI and a paramagnetic shift reagent”, L Zhang, A Martins, Y Mai, P Zhao, A Funk, V Clavijo-Jordan, S Zhang, W Chen, Y Wu & AD Sherry, Chem. Eur. J., 23, 1752-1756 (2017).

 

  1. “Zinc as an Imaging Biomarker of Prostate Cancer”, S-T Lo, AF Martins, V Clavijo-Jordan & AD Sherry, Israel J. Chem. 57, 854 –861 (2017).

 

  1. “Imaging insulin secretion from the mouse pancreas by MRI is improved by use of a zinc-responsive MRI sensor with lower affinity for Zn2+ ions”, AF Martins, V Clavijo-Jordan, F Bochner, S Chirayil, N Paranawithana, S Zhang, S-T Lo, X Wen, P Zhao, M Neeman, & AD Sherry, J. Am. Chem. Soc., 140, 17456–17464 (2018).

 

  1. “Advances in gadolinium-based MRI contrast agent designs for monitoring biological processes in vivo”, J Lux & AD Sherry, Curr. Opin. Chem. Biol., 45, 1-10 (2018).

 

  1. “A responsive MRI contrast agent for detection of excess copper(II) ions in mouse liver”, NN Paranawithana, AF Martins, V Clavijo-Jordan, P Zhao, S Chirayil, G Meloni & AD Sherry, JACS, 2019 Jul 17;141(28):11009-11018. doi: 10.1021/jacs.8b13493.

 

  1. “Synchrotron radiation X-Ray fluorescence mapping of zinc in healthy versus malignant prostate tissues provides new insights into the origin of glucose-stimulated zinc secretion first discovered by MRI”, V Clavijo Jordan, A Al-Ebraheem, T Geraki, AF Martins, S Chirayil, M Farquharson & AD Sherry, Inorg. Chem., 2019, doi: 10.1021/acs.inorgchem.9b01132.