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Dr. Palmer uses genomic, transcriptomic, and biochemical approaches to study antibiotic resistance in pathogenic bacteria. Her research focuses on microorganisms contributing to significant mortality and cost burdens in the health care industry.

She studies antibiotic resistance in, and the in vivo physiology of, pathogenic bacteria. The goals of her research are to: 1) characterize evolutionary and molecular mechanisms contributing to antibiotic resistance in the enterococci and to 2) use in vivo-relevant growth substrates to characterize the physiology of pathogenic bacteria, with each of these goals executed with an eye towards novel antimicrobial development.