BMES 2023

The Biomedical Engineering Society Annual Conference, held in Seattle, drew some of the brightest minds in biomedical engineering. Among the researchers who made significant contributions were members of the Jones Lab, who showcased their groundbreaking work through poster and podium talks.

Shuai presenting his research titled "Engineered Caner Models for In-Vitro Studies" at a Podium Talk at BMES — Shuai is presenting his research at a Podium Talk at BMES

Shuai Shao presented an intriguing study titled ‘A Microphysiological System Reveals Neutrophil Contact-Dependent Attenuation of Pancreatic Tumor Progression by CXCR2 Inhibition-Based Immunotherapy.’ This research shed light on the role of neutrophils in the progression of pancreatic cancer and the potential therapeutic benefits of CXCR2 inhibition. By utilizing a human cell-based microphysiological system, the study provided novel insights into the interactions between neutrophils and pancreatic tumor spheroids. The findings offer promising avenues for developing innovative immunotherapeutic strategies for pancreatic cancer.

In addition, Adam Heritier’s presentation on ‘A Microsystem-Based Approach for Monitoring Calcium Dynamics in Microglia during Inflammation’ captivated the audience. The study introduced a groundbreaking Calcium Monitoring Micro-Total Analysis System (CAM-μTAS) using microfluidics to investigate calcium dynamics in microglia following cytokine treatment.

This innovative approach demonstrated a 7-fold increase in calcium signaling, showcasing the potential of the CAM-μTAS chip as a valuable tool for studying cell interactions and calcium dynamics in various applications.

Adam is presenting his research — Shuai is presenting his research

The Jones Lab’s contributions at the conference exemplify the cutting-edge research being conducted in biomedical engineering and pave the way for new advancements in understanding and treating complex medical conditions.