The Dillon lab focuses on antibiotic resistant bacteria seeking to understand three main factors:
1) How does antibiotic resistance evolve
2) How can we treat antibiotic resistant infections
3) How can we prevent the evolution of antibiotic resistance in the future.
Our studies incorporate all classes of antibiotics, non-biological and biological antimicrobials, and novel drug and treatment approaches. We seek to understand the mechanistic basis for the activities of the antibiotics/antimicrobials/novel compounds that we study and define how they work in conjunction with each other and the host response during an infection. To do this we employ in vitro, ex vivo, and in vivo models that integrate concepts, principles, and techniques from microbiology, immunology, pharmacology, biochemistry, and systems biology.