Research

Genetic hearing loss

Electron micrograph of auditory efferent neuron

Electron micrograph of nuclear fragmentation observed in a medial olivocochlear efferent neuron taken from a congenitally deaf 6 month old homozygous Shaker2 mouse

Cochlear synaptopathy

Inner hair cell synapses from unexposed mouse
Unexposed

Confocal micrographs demonstrating the effects of noise on synapses between inner hair cells and spiral ganglion neurons of the cochlear at the 32kHz frequency place

Inner hair cell synapses from noise exposed mouse
2 hours of octave band (8-16kHz ) noise exposure at 98dB SPL

Serotonergic signaling in the auditory brainstem

Confocal micrograph demonstrating serotonergic boutons (green) apposed to cholinergic (red) medial olivocochlear efferent neurons

Serotonergic input onto auditory efferent neurons