Dr. Monu Joy
Research Scientist-II (Staff Crystallographer)
Department of Chemistry & Biochemistry, (Office: BE – 3.311)
School of Natural Science and Mathematics
The University of Texas at Dallas
800 W Campbell Rd, Richardson, TX, 75080, USA

E-mail: Monu.Joy@UTDallas.edu
Lab: BE 3.526

ORCID: 0000-0003-1947-9691
Scopus ID: 57189232720
Web of Science ResearcherID: B-6185-2016

Academic Training:

2018 – 2022 – PhD in Chemistry, Clarkson University, New York, USA.
2012 – 2014 – MSc in Chemistry, Mahatma Gandhi University, India.
2009 – 2012 – BSc in Chemistry, Mahatma Gandhi University, India.

Appointments:

01/2023 – Present: Research Scientist -II, Department of Chemistry & Biochemistry, The University of Texas at Dallas
08/2022 – Present: Affiliate – International Centre for Diffraction Data (ICDD)
08/2022 – 12/2022: Charles R. Shipley Jr. Endowed Research Assistant, Clarkson University
05/2022 – 05/2022: Visiting Student, X-ray Diffraction Facility, Department of Chemistry, Massachusetts Institute of Technology
07/2018 – 07/2022: Teaching Assistant, Clarkson University
07/2015 – 06/2018: Scientific Assistant (Service Crystallographer), Mahatma Gandhi University

Awards & Honors:

• Burroughs Wellcome Fund Travel Award – The 80th Annual Pittsburgh Diffraction Conference (2023)
• Affiliate – International Centre for Diffraction Data (ICDD) (2022-)
• American Crystallographic Association Travel Award (2022)
• Best Graduate Oral Presentation Award in Chemistry, Physics & Material Science, Clarkson University (2022)
• Shipley Endowed Fellowship Award – Department of Chemistry & Biomolecular Science, Clarkson University (2022)
• Best Graduate Poster Award – American Chemical Society Northern New York Meeting (2022)
• Ludo Frevel Crystallography Scholarship – International Centre for Diffraction Data (ICDD) (2022)
• Teaching Assistantship, Department of Chemistry & Biomolecular Science, Clarkson University, (2018 – 2022)
• Publons Peer Review Award for the top 1% of Reviewers in Chemistry (2018)
• Outstanding Reviewing Contribution Award for the Journal of Molecular Structure, (2017)
• Student Project Funding Award, Kerala State Council for Science Technology and Environment – (No.157/SPS/2013/CSTE) (2013)

Research Interests:

X-ray Crystallography | Computational Chemistry for Material Science | Structural Chemistry

Publications/Journal Cover Artworks:

2024

34 Synthesis and Characterization of Highly Fluorinated Hydrophobic Rare–Earth Metal–Organic Frameworks (MOFs)
@ Materials – MDPI
Muhammad Abbas, Bhargavasairam Murari, Simin Sheybani, Monu Joy and Kenneth J. Balkus, Jr.

33 Synthesis, structural, spectroscopic and theoretical insights into a new malononitrile derivative: A candidate for nonlinear optical applications
@ Journal of Molecular Structure – Elsevier
L Vidya, Shilpa Mangalassery, Aparna Raj, VM Aparna, S Neelima, Monu Joy, G Anilkumar, Gourisankar Roymahapatra, Sri Ram G Naraharisetty, ER Anabha, C Sudarsanakumar

32 An insight into structural, spectroscopic and nonlinear optical Application of a promising malononitrile derivative: (Z)-2-(3-chloro-3-(4-chlorophenyl)allylidene)malononitrile
@ Chemical Physics Impact – Elsevier
L Vidya, Avijit Ghosh, Aparna Raj, VM Aparna, S Neelima, G Anilkumar, Sri Ram G Naraharisetty, Monu Joy, ER Anabha, C Sudarsanakumar

31 Distinct Color Change of a Ho (III)-based Metal-Organic Framework upon Varying Incident Light Sources
@ Inorganic Chemistry Communications – Elsevier
Monu Joy, Okan Zafer Yeşilel, Mario Wriedt

2023

30 Encapsulation of Cobaltocenium Ions in a Zeolite-like Metal-Organic Framework
@ New Journal of Chemistry – RSC
Muhammad Abbas, Anne Marti, Arslan Umer, Monu Joy, Yaching Yang, Sue-Lein Wang and Kenneth J Balkus

29 Metal–Organic Framework as a Fluorescent and Colorimetric Dual-Signal Readout Biosensor Platform for the Detection of a Genetic Sequence from the SARS-CoV-2 Genome
@ Applied Materials & Interfaces – ACS
John C. Hadynski, Jaren Diggins, Zachary Goad, Monu Joy, Steven Dunckel, Petra Kraus, Thomas Lufkin, and Mario Wriedt

28 Water Harvesting Properties of A Zwitterionic Metal–Organic Framework
@ Molecular Systems Design & Engineering – RSC
Charlene C. VanLeuven, Juby R. Varghese, Monu Joy, Fletcher B. Dix, Kyle Duell, Donald Hartman and Mario Wriedt

2021

27 Force-Induced Near-Infrared Chromism of Mechanophore-Linked Polymers
@ Journal of American Chemical Society – ACS
Qingkai Qi, Gaganjot Sekhon, Richard Chandradat, Nnamdi M. Ofodum, Tianruo Shen, Jan Scrimgeour, Monu Joy, Mario Wriedt, Madhuri Jayathirtha, Costel C. Darie, Devon A. Shipp, Xiaogang Liu, and Xiaocun Lu

2020

26 Revealing the Role of Fluorine Pharmacophore in Chalcone Scaffold for Shifting the MAO-B Selectivity: Investigation of A Detailed Molecular Dynamics and Quantum Chemical Study
@ Journal of Biomolecular Structure and Dynamics – Taylor & Francis
Fisayo A. Olotu, Monu Joy, Mohamed A. Abdelgawad, Siju E. Narayanan, Mahmoud E. Soliman, Bijo Mathew

2019

25 Novel white light emitting dysprosium oxalate nanocrystals: Competing luminescence quenching by the features of Dy-Oxalate layered structure
@ Journal of Alloys and Compounds – Elsevier
Dinu Alexander, Kukku Thomas, RJ Manju Gopinath, Monu Joy, PR Biju, NV Unnikrishnan, Cyriac Joseph

24 Studies on the interaction between HSA and new halogenated metformin derivatives: influence of lipophilic groups in the binding ability
@ Journal of Biomolecular Structure and Dynamics – Taylor & Francis
Otávio Augusto Chaves, Bijo Mathew, Della Grace Thomas Parambi, Cosme Henrique CS de Oliveira, Dari Cesarin-Sobrinho, Balasubramanian Lakshminarayanan, Sadiya Najeeb, EK Nafna, Akash Marathakam, Md Sahab Uddin, Monu Joy, José Carlos Netto-Ferreira

23 Perspective design of chalcones for the management of CNS disorders: A mini-review
@ CNS & neurological disorders drug targets – Bentham
Bijo Mathew, DGT Parambi, VS Sivasankarapillai, J Suresh, GE Mathew, Monu Joy, A Marathakam, SV Gupta

22 Structural and spectroscopic investigations on the quenching free luminescence of europium oxalate nanocrystals
@ Acta Crystallographica Section C: Structural Chemistry – IUCr
Dinu Alexander, Kukku Thomas, Monu Joy, PR Biju, NV Unnikrishnan, Cyriac Joseph

21 In Vitro Study of the Interaction Between HSA and 4‐Bromoindolylchalcone, a Potent Human MAO‐B Inhibitor: Spectroscopic and Molecular Modeling Studies
@ ChemistrySelect – Wiley
Otávio Augusto Chaves, Rani Sasidharan, Cosme HC dos Santos de Oliveira, Sreedharannair Leelabaiamma Manju, Monu Joy, Bijo Mathew, José Carlos Netto‐Ferreira

20 An Environment-Friendly Synthesis of Piperonal Chalcones and Their Cytotoxic and Antioxidant Evaluation
@ Letters in Drug Design & Discovery – Bentham
Sanal Dev, Della Grace Thomas Parambi, Benncy Baby, Githa Elizabeth Mathew, Hendawy OM, Monu Joy, Shine Sudev, Bijo Mathew

2018

19 Structural features of Safinamide: A combined Hirshfeld surface analysis & quantum chemical treatment
@ Chemical Data Collections – Elsevier
Monu Joy, Bijo Mathew, C Sudarsanakumar

18 Rational Design of Pore Size and Functionality in a Series of Isoreticular Zwitterionic Metal–Organic Frameworks
@ Chemistry of Materials – ACS
Darpandeep Aulakh, Timur Islamoglu, Veronica F Bagundes, Juby R Varghese, Kyle Duell, Monu Joy, Simon J Teat, Omar K Farha, Mario Wriedt

17 Selected aryl thiosemicarbazones as a new class of multi-targeted monoamine oxidase inhibitors
@ MedChemComm – RSC
Bijo Mathew, Seung Cheol Baek, Jae Pil Lee, Monu Joy, PR Annie Rilda, Rugma V Randev, P Nithyamol, Vijitha Vijayan, Sini T Inasu, Githa Elizabeth Mathew, Krishnakumar K Lohidakshan, Girish Kumar Krishnan, Hoon Kim

16 Supramolecular framework of conjugated nitro-alkenes: Crystallographic and hirshfeld surface scan
@ Journal of Molecular Structure – Elsevier
Monu Joy, Nirmala Joseph, Varughese Mary, Vibin Jose, C Sudarsanakumar

15 Structural and optical profile of a multifunctionalized 2‐pyridone derivative in a crystal engineering perspective
@ Acta Crystallographica Section C: Structural Chemistry – IUCr
Monu Joy, ER Anabha, Subash Gopi, Bijo Mathew, Ajeesh Kumar S, Annie Mathews

14 Introduction of fluorinated environment on metformin. Evaluation of its serum-albumin interaction with molecular modelling studies
@ Journal of Molecular Liquids – Elsevier
Otávio Augusto Chaves, Bijo Mathew, Monu Joy, Krishnakumar K Lohidakshan, Akash Marathakam, José Carlos Netto-Ferreira

13 Efficient green luminescence of terbium oxalate crystals: A case study with Judd-Ofelt theory and single crystal structure analysis and the effect of dehydration on luminescence
@ Journal of Solid State Chemistry – Elsevier
Dinu Alexander, Monu Joy, Kukku Thomas, S Sisira, PR Biju, NV Unnikrishnan, C Sudarsanakumar, MA Ittyachen, Cyriac Joseph

2017

12 Refining the Structural Features of Chromones as Selective MAO-B Inhibitors: Exploration of Combined Pharmacophore-Based 3D-QSAR and Quantum Chemical Studies
@ ChemistrySelect – Wiley
Bijo Mathew, Sanal Dev, Monu Joy, Githa E Mathew, Akash Marathakam, Girish K Krishnan

11 Discovery of new class of methoxy carrying isoxazole derivatives as COX-II inhibitors: Investigation of a detailed molecular dynamics study
@ Journal of Molecular Structure – Elsevier
Monu Joy, Ahmed A Elrashedy, Bijo Mathew, Ashona Singh Pillay, Annie Mathews, Sanal Dev, Mahmoud ES Soliman, C Sudarsanakumar

10 Characterization of Thienylchalcones as hMAO‐B Inhibitors: Synthesis, Biochemistry and Molecular Dynamics Studies
@ ChemistrySelect – Wiley
Bijo Mathew, Gülberk Uçar, Clariya Rapheal, Githa E Mathew, Monu Joy, Kgothatso E Machaba, Mahmoud ES Soliman

09 Spectroscopic, zeta potential and molecular docking analysis on the interaction between human serum albumin and halogenated thienyl chalcones
@ Journal of Molecular Liquids – Elsevier
Otávio Augusto Chavesa, Bijo Mathewb, Dari Cesarin-Sobrinho, Balasubramanian Lakshminarayanan, Monu Joy, Githa Elizabeth Mathew, Jerad Suresh.

08 Synthetic Approaches to Various Class of Topoisomerase II Inhibitors
@ Mini Reviews in Organic Chemistry – Bentham
Sanal Dev, Nishad Gabhe, S.R. Dhaneshwar, Monu Joy, Bijo Mathew.

07 Monoamine oxidase inhibitory activity of methoxy-substituted chalcones
@ International Journal of Biological Macromolecules – Elsevier
Bijo Mathew, Githa Elizabeth Mathew, Gulberk Ucar, Monu Joy, EK Nafna, Jerad Suresh.

06 Anti-oxidant behavior of functiolised chalcone-a combined quantum chemical and crystallographic structural investigation
@ Journal of Molecular Structure – Elsevier
Bijo Mathew, Adebayo A Adeniyi, Monu Joy, Githa Elizabeth Mathew, Ashona Singh-Pillay, C Sudarsanakumar, Mahmoud ES Soliman, Jerad Suresh.

05 Pharmacophore Based 3D-QSAR Analysis of Thienyl Chalcones as a New Class of Human MAO-B Inhibitors. Investigation of Combined Quantum Chemical and Molecular Dynamics Approach
@ Journal of Physical Chemistry-B – ACS
Bijo Mathew, Adebayo A. Adeniyi, Sanal Dev, Monu Joy, Gulberk Ucar, Githa Elizabeth Mathew, Ashona Sing Pillay, Mahmoud E. S. Soliman.

04 Probing mechanism of α-formylketene dithioacetal towards the facile formation of functionalised pyrimidines: A structural approach
@ Journal of Molecular Structure – Elsevier
Monu Joy*, Adebayo A. Adeniyi, Annie Mathews, Bijo Mathew, S. Prasanth, Mahmoud E.S. Soliman, Jalaja J Malayan, E R Anabha.

2016

03 In Silico Quantum Chemical and Crystallographic Treatment of α‐Formylketene Dithioacetal towards the Elucidation of Its Structural and Optical Nature
@ ChemistrySelect – Wiley
Monu Joy*, Neethu Alex, Jalaja J Malayan, C Sudarsanakumar, Annie Mathews.

02 Exploration of chlorinated thienyl chalcones: A new class of monoamine oxidase-B inhibitors
@ International Journal of Biological Macromolecules – Elsevier
Bijo Mathew*, Abitha Haridas, Gülberk Uçar, Ipek Baysal, Adebayo A. Adeniyi, Mahmoud E.S. Soliman, Monu Joy, Githa Elizabeth Mathew, Baskar Lakshmanan, Venkatesan Jayaprakash.

01 Synthesis, Biochemistry, and Computational Studies of Brominated Thienyl Chalcones: A New Class of Reversible MAO‐B Inhibitors
@ ChemMedChem – Wiley
Bijo Mathew*, Abitha Haridas, Prof. Dr. Gülberk Uçar, Ipek Baysal, Monu Joy, Githa E. Mathew, Dr. Baskar Lakshmanan and Dr. Venkatesan Jayaprakash.